TopoTarget Major shareholder announcements Major Shareholder Announcement

TopoTarget A/S
Symbion
Fruebjergvej 3
DK 2100 Copenhagen
Denmark
Tel: +45 39 17 83 92
Fax: +45 39 17 94 92
CVR-nr: 25695771
www.topotarget.com


Copenhagen - 3 July, 2009 - TopoTarget A/S (OMX: TOPO) hereby announces that
the Company has today received a notification from BankInvest, that as of
result of BankInvest's participation in TopoTarget's rights issue,
corresponding to 75% of BankInvest's shareholding before the offering,
BankInvest's holdings of shares and voting rights are now less than 15% of
TopoTarget's total share capital and total number of voting rights. 


TopoTarget A/S

For further information, please contact:

Peter Buhl Jensen     Telephone      +45 39 17 83 92
CEO		      Mobile	     +45 21 60 89 22
	

Background information

About TopoTarget 
TopoTarget (OMX: TOPO) is an international biotech company headquartered in
Denmark, dedicated to finding ''Answers for Cancer'' and developing improved
cancer therapies. The company was founded and is run by clinical cancer
specialists and combines years of hands-on clinical experience with in-depth
understanding of the molecular mechanisms of cancer. 
TopoTarget has a broad clinical pipeline but is currently focusing on the
development of belinostat, which has shown proof of concept as monotherapy in
treating haematological malignancies and positive results in solid tumours
where it can be used in combination with full doses of chemotherapy, and is in
phase III in PTCL. TopoTarget's expertise in translational research is
utilizing its highly predictive in vivo and in vitro cancer models. TopoTarget
is directing its efforts on key cancer targets including HDACi, NAD+, mTOR,
FasLigand and topoisomerase II inhibitors. The company's first marketed product
Savene®/Totect® was approved by EMEA in 2006 and the FDA in 2007 and is
marketed by TopoTarget's own sales force in Europe and the US. For more
information, please refer to www.topotarget.com.