Anti-cancer activity of BI-505 demonstrated in animal model

Results presented at American Society of Hematology
Lund, Sweden–12 December 2011 – BioInvent International AB (OMXS: BINV) announced today that new preclinical data has been presented on its BI-505 programme that demonstrates anti-cancer activity in multiple myeloma and beneficial effect on bone density. The results were presented at the American Society of Hematology (ASH) Annual Meeting, San Diego, USA on Sunday 11 December 2011.

The study was conducted by researchers at the University of Utah, Salt Lake City, USA under the direction of Professor Guido Tricot. Compared to untreated controls, BI-505 treated animals showed a significant reduction (p-value <0.01) of tumour burden induced by primary human multiple myeloma cells as measured by human IgG levels. The active control, bortezomid (Velcade®*, Takeda/ Millennium) also showed significant effect (p-value <0.01) over the placebo control.

Svein Mathisen, President and CEO of BioInvent, said: “Current pharmaceutical regimes...

BioInvent

BioInvent International AB, which is listed on the O list of the Stockholm Stock Exchange (SAX:BINV), develops therapeutic antibodies against diseases where there is a significant unmet medical need. Antibodies are a str...

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